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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43488c00e23f59910e3e66ff403b5e3b7173fc024b170b1427e40053611e681c' 
  AND token = 'EzsEgosTDrOkyB6iBsYnfg8GKT/rNaI76DbWSLyhGLw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00060

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}