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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c33c1604383eff177364f4c283645575ed8be801d879f09a26d7377b52b9b14c' 
  AND token = 'f/MR6R8Yp+32L9svbDiXMSoyDRyOi6dAFfrgow4i8LY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}