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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ba21e97661be39d2cd13cd824bb404ddb0cd09b643126f99e449e300935af14' 
  AND token = 'Rf1ZZVfZyIL1yQoB2faSVnZKkIAsXRx7vm1w49sQL7g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00062

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}