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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c3ec899ecb5c71f85df3f7880c5318975f80577a196445f22e5a1923389a189f' 
  AND token = 'VoDY13B+O1/PaBgLU9v6/U5V1YaSLbx1FMMXr9O2HuY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}