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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a199fbac67c6fa7663dd9d2726686ae15591ce8644d4a03e191fa37eb7938672' 
  AND token = 'ZTcFZtPd66yu0gt5nRQg+RMkOTxVoe/8TIL5gmdYmq8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}