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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '173c96358418fe2675e50e915a5d4d0d100514138362744f35211a2a71fc32f0' 
  AND token = '+n12vpCCIL6VD58mmiyO5K4S+HJruM83oNZYkZyppf0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}