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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a354669fd93c2ed3049c400e97b2b94d1b56647a094e753daf05de19b4c3f4a4' 
  AND token = 'Tv+AS7qJOhjmNiYi6EbOTuLP2rbtfSiRDXr0llwVX54=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}