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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01bf95222e939d45bcd69c57d2ac58eed56da89766e6a84342c3db323a707560' 
  AND token = '7Hx01cnQgO5mQCUeRXWI0MKv2UFq19PbUcRbRqu0Dxk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}