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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e2f29958497b7311fb22fd6c29653805e3470c6dc4be1d769964f0648c4f189' 
  AND token = 'XoF14PEvnUriPmk/7akCyw5LeytjckGOMs4q24wWL74=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}