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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81e8cd07c6a146394d9a6e16ffb412c37a3b1014d089a3b34aac6290211a7b56' 
  AND token = 'JBUzpE7HQEdmWQrzLtXIkVjcnBASsXYBokbCJAZDTZ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}