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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a19a8e850806fe66f8e80082aa814d21305921d8b448d48461e1b73f43f2bfa5' 
  AND token = 'wlOcYeaPAxK9+O/O8yIGqeg+MYmgZ1bXLH5hC80927Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}