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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '824bf40184b8dd9c4b42be3ffd3aae5277d6f78e3d774993476e254a0acd72d1' 
  AND token = 'gSbc1QV+zyVj++csRnxrlm8we11q5HKSRZgiv158fiQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}