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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2fe12a1a21aa007fdaf281d02777b0f5796dc0be956e3ed85cc4d5b8b40f8b47' 
  AND token = 'kXbX2eniVq4Yg7acId0N6K1rdh5XXwAwveGxGmjH8vY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}