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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7092f9339d1e04ae7005b765397fa47dfb280381867bbe81dce6a9bfff086899' 
  AND token = 'DSe88Dv0393Qhr+XAmR8v4UY1D4umpjEMPMS1hYLiNo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}