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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9b22606cedc0b3fef934f8c8ee9f54f724eba3bf37f88748eac9da2c12f85c0b' 
  AND token = 'h9Jw2zBWcIjsB1EXhkjBwDt9JmdGr0RvPkkVwMo9Wlk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}