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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d9c854b1ce975df26ce6e0677a920aaa8703530a0447cf2100e17bd9cf26d8a' 
  AND token = 'DRy7SKIHq2UfWDzs8GAs0sa7UtFj0NIVYpqvbAUEAqM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00058

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}