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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c131acd2540f7e944940513d52960bc35f1e873c0942bb1f2cef09dc632b90b' 
  AND token = '15QKPRyMbZlQ+tWlDRTRpj2ibQ7uwZZCHYsAyENOjAI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}