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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a69ae0025b3411e6f65c30b0c0574e046bf5b9de76dc48e401ad1af9dd3fe097' 
  AND token = 'fyMQ+msF7rc/ra+4KjQuJMqYl6zjDPME+lTpx6PMlcM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}