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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4948f21f143a9aa1d80334626dcc6b03271672d5f4368d0f9b8a6ca426810f10' 
  AND token = 'boBH4TUdkAnyjAl7RBBhDGC34c/QOp0zdtILkHl7mic=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}