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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45178fa8c130dc949119cbfd0b7fc117627717c7c053b69cae276c8b29575f74' 
  AND token = 'wmOY8E4xxBDxhem1PWDNi2U9PqnQfXfARdQkbQdSmv0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}