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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c293e6889b197dcb76e9de0bbd79d7ca5566bf80f6609bdd4968f13a5f2c2bd' 
  AND token = '0JCotjOOwCH8S0hCCGcGhuyvG1+wWFChP80c4PJd3oM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}