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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ec8011d67ce9c38befec178ac4789e097a64a1030bb2c18363aba99b70f762d' 
  AND token = '86rBUG4qlHvZtUW+3UXp3FmGvbXx5BJhII09WaNKJGQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}