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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c09778aa237da7e6be3ccdd5c8db911ad86f4df99609e81613906d47aaff4afd' 
  AND token = 'a1GgWZX6hbSyxZzvFnfOlbFtzTgGTbBvBHUhBQUB/tk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}