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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '17ab247104c36b454b246a121d9c0ed4163ac25a58c9e9fbe56849b3322fded1' 
  AND token = 'KgK8A6oKuDU+RJo8uV03x3QcMb7803OIh7MZuI9DKZ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}