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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e9f709243885cfe59f2eb25f1be12643d6200f50d9d5a9cfa4c935d9f35ccd2' 
  AND token = 'CvEaZbV1kNAisANs8mKqvZg6P1MPzPblLX4FpzBLAdQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}