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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18cabf962d1cf7cbfd9daf0d1df42bb50ab158b49cda2c8e505abd93d839b669' 
  AND token = 'X4n8opXTTBeLU1XlKpnlRvMwxJZ4zI62QjTrfP2tQ1I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}