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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a0d0a0e94622bf002a3bd3e4b556a27634c4a960c7a7c07386763c358cbb3e26' 
  AND token = 'BIsxcuxjr7Uz3Qu+RfA6Xt2EGFUH/O/3VBMlc+j7WqY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}