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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d5234dfec74b3bc1b882975ab6a86fa9f2d9752465d532e89550f5815597a35' 
  AND token = 'lv1EJQYCBA1PMFyHZ4qwIojAbqSsBcnEYFoEwc359fw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}