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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9358f8d97a6fe2139293b5762680dfedba17985cb310c5f6d2147bb465d69a06' 
  AND token = 'vpYmOfDKmIDzCUaHA1YrMqPitEZG93kdkkrRaI5+Oog=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}