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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48a40de4f4fa2605c7a8a1ad902a387154a38071e09545dab0eb97f75d7a4f12' 
  AND token = 'T+CibCEvhy+s6UJH0bIm2DoLvAq9EYahd0dxAGbLmiY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}