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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed801a8b772fa135a9808cd1dfd07454daa74ee5152ea2a8caff97b1d6946ddd' 
  AND token = 'uJQSsLfIrgbuXH10vK80+ie0DfKZ11tmCz2LsqbgbYE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}