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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d7f2c18ce5e2ae3fbd65cf2fcd0d44d728c3baea8a8e7f414d587e1397b3eb1' 
  AND token = 'pITPq3tv1Zlcfvq/VdnurX1tLBFhrEc2wJz8KZi2/Xk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}