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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5b50ec05c2d2c24b9567afb17278ffd2af056292fe8ade7da896ca6ec3d6fef' 
  AND token = '2mioIo+NNuQtWmYSTxP8SVUGJsTmCqjGu6+vZ7BMPek=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}