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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '99a46d6d2857dd067d02f930bad951522313b5fc00f28f7c0806738f6f9bff22' 
  AND token = 'hPr5J4ShaxEmzKUH3twdArpSlfz4eZmzYU3+iFg0dMA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}