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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b169aa81cb4d5cb430da11c9b4a4d0109eb8d51c9ecfd5f0568e1baefdf6531' 
  AND token = 'I5v3HC+hfo+EL2mWCVxxhDVcb5sLDSBx5KN9NjxWosA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}