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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0249325e1fcfa47e0053698c68e601c3683caf4c4278c5ac1615f78e0e35bb21' 
  AND token = '3GxtvVZymjOAEj8B8K9YwzSweZHPlXNpvppNHpftSz8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}