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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c8c11e3505d641c567fa6a9ff8d03801b750efd1e64e8652a6c39ac182e9de7' 
  AND token = 'K2E+O07zF1fulm7QmAM9CYEn4jgHgH7WGMtFTiLfJMs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}