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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4195e7be2f58055bc71c2efe760784b2f3917018246d6450c099fb9e49a7607e' 
  AND token = 'rSwbr8Dr0lKhJx7MWZ4dj9bNBmcCtir46yTPvrZ5vpo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}