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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4a1844d05f23c0a15208cd88860b6838544ce04362b0d825e52a39a30ee54e3' 
  AND token = '5y1g3LpxiR0FJ2Nmp0Etgkxxk/pyqO5NcjZSVT0RToo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00065

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}