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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9250cb2a5142ef0dfe9a86e6478c9417dcc130165717161b7ee0a00908170040' 
  AND token = 'm3/tDXz4qC2aRzk35DsuK8NdjsJo2guowzObWcSmJyE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}