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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a309d1cf9ac2bd1cd17797b7d282630b167b073b96d6df71d451670655653911' 
  AND token = 'gDD5U5+t0z6gL7W5KkTQLh7XKKemMcVpnaqiTi4FA2Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}