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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fc49994555b0c54715c20785998b4027ebc41b1da30ee51a793ec043adc20c80' 
  AND token = '5vrT31hTq3CqxzTCKTVLT4DzonaTSbXXaVjM8TZ59yU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}