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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8af9c50bd488587667e2fd986fbceffb6f5f2b47dfc40e4522f4a96b742da0ab' 
  AND token = '//tFuUk/rRT/zO/IwGRQNVjhjiZooOUyvxSV5uFWnzA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}