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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e9727bd1c24f170a3272fa4b31072998c44efafdbfb94c71c8f9148b84b0d22' 
  AND token = 'YHKfymEPPR4u9zu7CD2u81U0Dn3FgLJdMlpYgZ+Y2ZU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00065

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}