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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '225e7b4c8e7ec6127e8076d5a0ecae8b4e5c0e380685fcaa3a65c86133bea10f' 
  AND token = 'JRN9DaHCebtye2yMlPsCbqPiMLibt1n3XpIYqBHL9C0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00077

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}