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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b602789ff44b20db8de2a3df78b0a4f84ffc32717f2c9654e7c8e549a8e326b2' 
  AND token = 'd2pFJrXnOZ33QVLwcSRRK0yXOM2B4DWjqcdN1LXk/EM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}