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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e39407eb41fd3f083cf505e3fedabb96a15a385ced5bb19bce6ab95d89855a30' 
  AND token = 'nnuj7OUTtgTTNMk6epBm3radTVbUAteZlY9ZgvC5NQQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00070

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}