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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e300bc4aafea7e869305d143ee931703a6f6409132d88acc1c288903e9c43db' 
  AND token = 'GY4wF/erl/r9BEcKDTe2/3W1aJxGOAeruIqUhiXcwwg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}