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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b819f2035bdd537e5602c7a164ea458fe112804c33bbf5217f84e1c9f3c6880c' 
  AND token = 'NtIRyWZsCl7kqCQdMcMkfp31AMsF73gRbdXeT2F7aIg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}