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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8601f219beac0a5b2af4cd1cfd9920e17e9be8ec157267b9519eaf2d19d6d57c' 
  AND token = 'vsmR9XPAqMG3yCry/tx5YXt/EPMVEYOZ6ofaZ2fyPCI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}